Essential tremor in Parkinson's disease kindreds from a population of similar genetic background
Identifieur interne : 000A96 ( Main/Exploration ); précédent : 000A95; suivant : 000A97Essential tremor in Parkinson's disease kindreds from a population of similar genetic background
Auteurs : Cleanthe Spanaki [Grèce] ; Andreas Plaitakis [Grèce]Source :
- Movement Disorders [ 0885-3185 ] ; 2009-08-15.
Descripteurs français
- Wicri :
- topic : Crète.
English descriptors
- KwdEn :
Abstract
To investigate the possible association between essential tremor (ET) and Parkinson's disease (PD) we conducted a prospective clinical and epidemiological study in a population of similar genetic background. The first‐degree relatives of 303 PD probands and 249 controls from Crete were evaluated for the presence of ET. In addition, the possible co‐occurrence of ET and PD in the same family or in the same individual was investigated. Results showed that ET was present in the relatives of PD patients more often than in those of controls (OR:3.64, P < 0.001). The risk was even greater (OR: 4.48) when the affected proband had tremor‐dominant or mixed PD. Female relatives and siblings of PD patients were more likely to have ET than male relatives and parents of PD patients (OR: 4.36 v/s 2.89 and 4.49 v/s 2.74, respectively). Twelve subjects had both ET and PD phenotypes. While this may have occurred by chance, a number of families were identified in which ET and PD were coinherited through the same parental line. Hence, in certain families ET and PD are genetically related probably sharing common hereditary predisposition. © 2009 Movement Disorder Society
Url:
DOI: 10.1002/mds.22655
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Essential tremor in Parkinson's disease kindreds from a population of similar genetic background</title>
<author><name sortKey="Spanaki, Cleanthe" sort="Spanaki, Cleanthe" uniqKey="Spanaki C" first="Cleanthe" last="Spanaki">Cleanthe Spanaki</name>
</author>
<author><name sortKey="Plaitakis, Andreas" sort="Plaitakis, Andreas" uniqKey="Plaitakis A" first="Andreas" last="Plaitakis">Andreas Plaitakis</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:A5975BA027E5B1AFC277C9FCF673F12AA03E2023</idno>
<date when="2009" year="2009">2009</date>
<idno type="doi">10.1002/mds.22655</idno>
<idno type="url">https://api.istex.fr/document/A5975BA027E5B1AFC277C9FCF673F12AA03E2023/fulltext/pdf</idno>
<idno type="wicri:Area/Main/Corpus">001720</idno>
<idno type="wicri:Area/Main/Curation">001484</idno>
<idno type="wicri:Area/Main/Exploration">000A96</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Essential tremor in Parkinson's disease kindreds from a population of similar genetic background</title>
<author><name sortKey="Spanaki, Cleanthe" sort="Spanaki, Cleanthe" uniqKey="Spanaki C" first="Cleanthe" last="Spanaki">Cleanthe Spanaki</name>
<affiliation wicri:level="1"><country xml:lang="fr">Grèce</country>
<wicri:regionArea>Department of Neurology, University of Crete, Medical School, Heraklion, Crete</wicri:regionArea>
<wicri:noRegion>Crete</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Plaitakis, Andreas" sort="Plaitakis, Andreas" uniqKey="Plaitakis A" first="Andreas" last="Plaitakis">Andreas Plaitakis</name>
<affiliation wicri:level="1"><country xml:lang="fr">Grèce</country>
<wicri:regionArea>Department of Neurology, University of Crete, Medical School, Heraklion, Crete</wicri:regionArea>
<wicri:noRegion>Crete</wicri:noRegion>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series><title level="j">Movement Disorders</title>
<title level="j" type="sub">Official Journal of the Movement Disorder Society</title>
<title level="j" type="abbrev">Mov. Disord.</title>
<idno type="ISSN">0885-3185</idno>
<idno type="eISSN">1531-8257</idno>
<imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher>
<pubPlace>Hoboken</pubPlace>
<date type="published" when="2009-08-15">2009-08-15</date>
<biblScope unit="volume">24</biblScope>
<biblScope unit="issue">11</biblScope>
<biblScope unit="page" from="1662">1662</biblScope>
<biblScope unit="page" to="1668">1668</biblScope>
</imprint>
<idno type="ISSN">0885-3185</idno>
</series>
<idno type="istex">A5975BA027E5B1AFC277C9FCF673F12AA03E2023</idno>
<idno type="DOI">10.1002/mds.22655</idno>
<idno type="ArticleID">MDS22655</idno>
</biblStruct>
</sourceDesc>
<seriesStmt><idno type="ISSN">0885-3185</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Crete</term>
<term>Parkinson's disease</term>
<term>essential tremor</term>
<term>pedigrees</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Crète</term>
</keywords>
</textClass>
<langUsage><language ident="en">en</language>
</langUsage>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="fr">To investigate the possible association between essential tremor (ET) and Parkinson's disease (PD) we conducted a prospective clinical and epidemiological study in a population of similar genetic background. The first‐degree relatives of 303 PD probands and 249 controls from Crete were evaluated for the presence of ET. In addition, the possible co‐occurrence of ET and PD in the same family or in the same individual was investigated. Results showed that ET was present in the relatives of PD patients more often than in those of controls (OR:3.64, P < 0.001). The risk was even greater (OR: 4.48) when the affected proband had tremor‐dominant or mixed PD. Female relatives and siblings of PD patients were more likely to have ET than male relatives and parents of PD patients (OR: 4.36 v/s 2.89 and 4.49 v/s 2.74, respectively). Twelve subjects had both ET and PD phenotypes. While this may have occurred by chance, a number of families were identified in which ET and PD were coinherited through the same parental line. Hence, in certain families ET and PD are genetically related probably sharing common hereditary predisposition. © 2009 Movement Disorder Society</div>
</front>
</TEI>
<affiliations><list><country><li>Grèce</li>
</country>
</list>
<tree><country name="Grèce"><noRegion><name sortKey="Spanaki, Cleanthe" sort="Spanaki, Cleanthe" uniqKey="Spanaki C" first="Cleanthe" last="Spanaki">Cleanthe Spanaki</name>
</noRegion>
<name sortKey="Plaitakis, Andreas" sort="Plaitakis, Andreas" uniqKey="Plaitakis A" first="Andreas" last="Plaitakis">Andreas Plaitakis</name>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/ParkinsonV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000A96 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000A96 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Sante |area= ParkinsonV1 |flux= Main |étape= Exploration |type= RBID |clé= ISTEX:A5975BA027E5B1AFC277C9FCF673F12AA03E2023 |texte= Essential tremor in Parkinson's disease kindreds from a population of similar genetic background }}
This area was generated with Dilib version V0.6.23. |